V. Giliberti, R. Polito, E. Ritter, M. Broser, P. Hegemann, L. Puskar, U. Schade, L. Zanetti‐Polzi, I. Daidone, S. Corni, F. Rusconi, P. Biagioni, L. Baldassarre, M. Ortolani
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Difference mid-IR nanospectroscopy on individual patches of purple membranes: the proton pump activity of bacteriorhodopsin at the nanoscale
Conformational changes of the light-sensitive membrane receptor and proton pump bacteriorhodopsin is investigated by tip-enhanced mid-infrared nanospectroscopy on individual cell membrane patches, with a dramatic increase of sensitivity (in terms of number of probed molecules) compared with standard mid-infrared spectroscopy.
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