5-氟尿嘧啶诱发的白质脑病。

IF 5.6 2区农林科学 Q1 AGRONOMY Rice Science Pub Date : 2023-10-01 Epub Date: 2023-01-12 DOI:10.4103/jcrt.jcrt_2165_21

Muthu Manikandan, Biju Azariah, Rajiv Sharma

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摘要

摘要：5-氟尿嘧啶（5FU）诱发的白质脑病的发病率是

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5-Fluorouracil-induced leukoencephalopathy.

Abstract: The incidence of 5-Fluorouracil (5FU)- induced leukoencephalopathy is <5% among the patients treated with this agent. It may present with disorientation, confusion, agitation, seizure, and coma. It should be suspected when patients present with any of these symptoms during or immediately after 5FU chemotherapy. Early detection of drug-induced leukoencephalopathy is important as the clinical symptoms can be reversed by early discontinuation of the drug. Therefore, clinicians should be aware of the possibility of this adverse neurologic effect of 5FU. We describe the case of a 35-year-old female with carcinoma esophagus with 5FU-induced leukoencephalopathy.

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来源期刊

Rice Science Agricultural and Biological Sciences-Agronomy and Crop Science

CiteScore

8.90

自引率

6.20%

发文量

审稿时长

40 weeks

期刊介绍： Rice Science is an international research journal sponsored by China National Rice Research Institute. It publishes original research papers, review articles, as well as short communications on all aspects of rice sciences in English language. Some of the topics that may be included in each issue are: breeding and genetics, biotechnology, germplasm resources, crop management, pest management, physiology, soil and fertilizer management, ecology, cereal chemistry and post-harvest processing.