中国黑龙江省重症监护病房非肝性高血糖横断面调查

Yue Li, Zhipeng Yao, Tong Li, Hongliang Wang
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摘要

简介:血氨检测和非肝性高氨血症(NHH)在患者治疗和预后中的重要性在临床上一直被忽视。本研究的目的是评估中国黑龙江省重症监护病房成人NHH的病因、诊断、治疗和预后。为了解决这一问题,我们设计了一项省级严重成人NHH调查,包括其病因、危险因素、发病率、预后和治疗策略。方法:采用全省横断面调查的方法,涉及黑龙江省5个城市。所有符合纳入标准的患者均有资格申请参加研究,包括基线人口统计学,临床表现以及与诊断和治疗相关的随访。结果:本研究招募的患者总数估计达到759例。所有符合纳入标准的患者均有资格申请参加研究,包括基线人口统计学,临床表现以及与诊断和治疗相关的随访。结论:本研究有望为制定更加科学、规范的NHH诊疗方法提供理论依据。伦理与传播:获得哈尔滨医科大学第二附属医院伦理委员会伦理批准(注册号KY2019-184)。本次审查的结果将通过同行评议的出版物和科学报告进行交流。试验注册号:ChiCTR1900026632。
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A Cross-Sectional Survey on Nonhepatic Hyperglycemia in Intensive Care Unit, Heilongjiang Province, China
Introduction: The importance of blood ammonia detection and nonhepatic hyperammonemia (NHH) in the treatment and prognosis of patients has been neglected clinically. The purpose of this study was to evaluate the etiology, diagnosis, treatment, and prognosis of NHH in intensive care unit adults in Heilongjiang province, China. To solve this problem, we designed a provincial-level survey of severe adult NHH, including its etiology, risk factors, incidence, prognosis, and treatment strategies. Methods: The present study refers to a cross-sectional survey of the whole province, involving five cities in Heilongjiang province. All patients who met the inclusion criteria were eligible to apply to participate in the study, which included baseline demographics, clinical presentation, and follow-up related to diagnosis and treatment. Results: The total number of patients to be recruited in this study was estimated to reach 759. All patients who met the inclusion criteria were eligible to apply to participate in the study, which included baseline demographics, clinical presentation, and follow-up related to diagnosis and treatment. Conclusion: This study is expected to provide a theoretical basis for the development of more scientific and standardized NHH diagnosis and treatment methods. Ethics and Dissemination: Ethical approval was obtained from the ethics committee of The Second Affiliated Hospital of Harbin Medical University (registration number KY2019-184). The findings of this review will be communicated through peer-reviewed publications and scientific presentations. Trial Registration Number: ChiCTR1900026632.
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