治疗多发性硬化症的前景:不久的将来

Gennadii E. Sheiko, A. Belova, M. N. Kudykin
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引用次数: 0

摘要

多发性硬化症(MS)是一种广泛的中枢神经系统免疫功能障碍-神经退行性疾病,病因不明。尽管在治疗多发性硬化症方面取得了重大成就,但进展性残疾和早期死亡率的水平仍然高得惊人。本文的主要目的是对治疗多发性硬化症的新药物进行详细的描述。本文给出了临床前和临床试验的数据,并描述了正在开发的药物的推测机制。开发治疗多发性硬化症的新方法是现代科学研究的热点。本综述重点介绍了目前正在进行临床试验的新治疗方法,并可能在不久的将来进入临床实践。
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Prospects in treatment of multiple sclerosis: near future
Multiple sclerosis (MS) is a widespread dysimmune-neurodegenerative disease of the central nervous system of unclear etiology. Despite significant achievements in the therapy of MS, the level of progressing disability and early mortality remains alarmingly high. The main aim of the given review is to give a detailed description of new promising medical drugs for treatment of MS. In the article the data of preclinical and clinical trials are given, presumptive mechanisms of the medical drugs under development are described. Development of new therapeutic approaches in treatment of MS is of great interest in modern science. The given review highlights new methods of treatment that are now undergoing clinical trialы and will probably come to the clinical practice in the near future.
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