用辛伐他汀和MTA直接盖髓:边缘适应扫描电镜研究

IF 0.5 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Giornale Italiano di Endodonzia Pub Date : 2021-06-11 DOI:10.32067/GIE.2021.35.01.25
M. Sharaan, A. Aly, E.M Elddamony, M. Hashem
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引用次数: 1

摘要

目的:探讨辛伐他汀(Smv)、三氧化二矿骨料(MTA)及两种材料联合应用于犬牙体直接盖髓(DPC)后3个月的边缘适应性。方法:随机对2只犬的上颌、下颌18个门牙进行DPC手术。用Smv或Smv+MTA或MTA覆盖V类牙髓暴露。采用中间修复材料(Intermediate Restorative Material, IRM)修复所有牙槽。在90天的随访期后,对狗实施安乐死,并将门牙切成两半,在扫描电子显微镜下进行研究。对DPC材料与牙本质和牙髓之间的界面进行间隙平均占DPC材料总面积的百分比检查。结果:Smv组与Smv+MTA组比较,差异有统计学意义(p0.05)。Smv+MTA组的平均间隙面积百分比值最高(3.750±1.802),其次是MTA组(2.121±1.166),Smv组的平均间隙面积百分比最低(1.339±1.271)。结论:辛伐他汀具有良好的边际适应性,可作为DPC材料使用。
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Direct pulp capping using Simvastatin and MTA in dogs’ teeth: marginal adaptation SEM study
Aim: To investigate the marginal adaptation of Simvastatin (Smv), Mineral Trioxide Aggregate (MTA), and the combination of the two materials after direct pulp capping (DPC) in dogs’ teeth after three months. Methodology: DPC was performed at random on 18 maxillary and mandibular incisors of two dogs. The pulpal exposures in class V cavities were capped with either Smv or Smv+MTA or MTA. All cavities were restored with Intermediate Restorative Material (IRM). After a 90-day follow-up period, the dogs were euthanised and the incisors were sectioned into two halves and studied under the scanning electron microscope (SEM). The interface between the DPC materials and pulp as well as dentine is examined for gap mean percentage to the total area of the DPC material. Results: There was a statistically significant difference between Smv and Smv+MTA groups (P 0.05). The highest mean gap area percentage value was recorded in the Smv+MTA group (3.750±1.802) followed by the MTA group (2.121±1.166) while the lowest gap percentage was recorded in the Smv group (1.339±1.271). Conclusions: Simvastatin showed a good marginal adaptation property that encourages its use as DPC material.
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来源期刊
Giornale Italiano di Endodonzia
Giornale Italiano di Endodonzia DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
0.90
自引率
25.00%
发文量
0
审稿时长
24 weeks
期刊介绍: The Giornale Italiano di Endodonzia was founded in 1987 and is the official journal of the Italian Society of Endodontics (SIE). It is a peer-reviewed journal publishing original articles on clinical research and/or clinical methodology, case reports related to Endodontics. The Journal evaluates also contributes in restorative dentistry, dental traumatology, experimental pathophysiology, pharmacology and microbiology dealing with Endodontics.
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