在类风湿关节炎患者中使用一种新型白细胞介素-6受体抑制剂来利单抗的实际问题

P. Novikov, E. Kuznetsova, N. Nosova, T. Shevtsova, M. Litvinova, V. Logina, S. Moiseev
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引用次数: 0

摘要

来利单抗是一种靶向白细胞介素-6受体的单克隆抗体,具有有效的抗炎活性。来利单抗治疗类风湿关节炎的有效性和安全性在多中心、双盲、安慰剂对照临床试验AURORA和SOLAR中得到证实。作者介绍了两例类风湿性关节炎患者,他们成功地用利来单抗治疗,并讨论了在临床实践中使用利来单抗的各种问题。
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Practical issues in the use of levilimab, a novel interleukin-6 receptor inhibitor, in patients with rheumatoid arthritis
Levilimab is a monoclonal antibody targeting interleukin-6 receptors and having a potent anti-inflammatory activity. Efficacy and safety of levilimab for treatment of rheumatoid arthritis were established in multicenter, double blind, placebo-controlled clinical trials AURORA and SOLAR. The authors present two patients with rheumatoid arthritis who were treated successfully with levilimab and discuss various issues of its use in clinical practice.
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