青叶和香茅鲜叶的化学成分、杀幼虫活性和杀软体活性Stapf

Revista Colombiana de Ciencias Químico-Farmaceúticas-Unal, P. V. S. Rosa, Paulo Sérgio Santos Júnior, Irlane Thais Pereira de Sousa, Igor Santos da Silva, Wilma Karlla dos Santos Farias, Laurilene dos Santos Souza, Danielly Fonseca, Ari Pereira de Araújo Neto, G. O. Everton
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引用次数: 1

摘要

前言:本研究主要评价了泽柏属(Alpinia zerumbet)和香茅属(Cymbopogon citratus)精油的化学性质、杀幼虫活性和对光秃血吸虫(Biomphalaria glabrata)的杀螺活性。Stapf。采用水蒸气蒸馏法提取精油,采用气相色谱-质谱联用技术对精油进行化学表征。理化参数参照巴西药典进行测定。毒性试验采用青蒿碱浸出液进行生物试验,经本试验批准的EOs进行生物学特性评价。方法学:采用WHO推荐的方法测定杀螺活性,采用Reed&Muench法测定其对钉螺的LC50。两种精油均表现出较低的毒副作用,具有较强的杀虫和杀虫生物学性能。其中,杀虫活性的LC50分别为40.63 mg·L-1和33.94 mg·L-1。结果:两种精油均有杀幼虫和杀软体动物的作用,效果令人满意。结果表明,评价的环氧乙烷是由具有潜在的杀虫和杀幼虫生物活性的物质组成的,因此可以促进和鼓励其应用。
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Chemical constituents, larvicidal activity and molluscicidal from fresh leaves of Alpinia zerumbet (Pers.) and Cymbopogon citratus (DC.) Stapf
  Introduction: This study evaluated the chemical characterization, larvicidal activity and molluscicidal activity in front of the snail transmitting schistosomes (Biomphalaria glabrata) of the essential oils of Alpinia zerumbet and Cymbopogon citratus (DC.) Stapf. The essential oils (EOs) were extracted by hydrodistillation, with chemical characterization through Gas Chromatography coupled to mass spectrometry (GC-MS). The physical-chemical parameters were determined according to the Brazilian Pharmacopoeia. The toxicity test followed the bioassay with Artemia salina Leach, the EOs approved in this assay followed to evaluate their biological properties. Methodology: for molluscicidal activity, the methodology recommended by the WHO was performed, and the LC50 of the EOs was performed for their action in the face of the snail obtained by the Reed&Muench method. Both EOs showed low toxicity, and thus were evaluated for the biological properties larvicidal and molluscicidal .Alpinia zerumbet EO showed molluscicidal activity with LC50 of 40.63 mg·L-1 and Cymbopogon citratus EO 33.94 mg·L-1. Results: Both EOs showed larvicidal and molluscicidal potentials against the organisms tested, showing satisfactory results for their action. The results indicate that the evaluated EOs are composed of substances that promote and encourage their application due to their potential for molluscicidal and larvicidal biological activity.
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