风湿病和内皮功能

Варвара Леонидовна Марчук, Николай Васильевич Соботюк, С. В. Бочанцев
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引用次数: 1

摘要

这篇综述分析了慢性炎症性疾病在诱导内皮功能障碍中的作用,作为加速心血管系统动脉粥样硬化变化的一个因素。讨论了非侵入性技术在评估内皮功能障碍以检测儿童和青少年风湿性关节炎临床前动脉粥样硬化变化中的重要性。据推测,在患有风湿性疾病的儿童和青少年中,内皮功能障碍的早期迹象的检测,以及传统的风险因素,应该成为预防随后年龄阶段不良心血管事件策略的一个组成部分。
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РЕВМАТИЧЕСКИЕ ЗАБОЛЕВАНИЯ И ЭНДОТЕЛИАЛЬНАЯ ФУНКЦИЯ
The review analyzes the role of chronic inflammatory diseases in the induction of endothelial dysfunction as a factor in the acceleration of atherosclerotic changes in the cardiovascular system. The importance of non-invasive techniques for evaluating endothelial dysfunction to detect preclinical atherosclerotic changes in children and adolescents with rheumatic was discussed. It is postulated that the detection of early signs of endothelial dysfunction in children and adolescents with rheumatic diseases, along with traditional risk factors, should become an integral part of the strategy for preventing adverse cardiovascular events in subsequent age periods.
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