生物可吸收支架:当前概念和未来技术

D. Dash, Shahid Merchant
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引用次数: 0

摘要

经皮冠状动脉介入治疗(PCI)中引入药物洗脱(DES)支架对冠状动脉疾病的患者管理产生了重大影响,被称为介入心脏病学继球囊血管成形术和裸金属支架两次革命之后的“第三次革命”。生物可吸收支架/支架(BRS)技术发展的动力来自于适应性重塑、血管舒张恢复、后期管腔扩大以及保留在先前PCI部位进行未来冠状动脉旁路移植术的潜力。此外,由于晚期和极晚期支架血栓形成的固有风险,BRS可能提供了一种解决方案,近年来人们对其的兴趣、宣传和希望都有所提高。在这篇综述中,我们旨在阐明各种BRS的优缺点,并展望未来。
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Bioresorbable scaffolds: current concepts and future technology
The introduction of the drug-eluting (DES) stent to percutaneous coronary intervention (PCI) had a significant impact on patient management of coronary artery disease and has been called the “third revolution” in interventional cardiology after the first 2 revolutions of balloon angioplasty and bare-metal stents. The promise of adaptive remodeling, restoration of vasomotion, late luminal enlargement, and retained potential for future coronary artery bypass grafting at the site of previous PCI has been the driving force behind bioresorbable stent/scaffold (BRS) technology development. Moreover, because of the inherent risk of late and very late stent thrombosis, BRS potentially offers a solution and recent years have seen heightened interest, hype, and hope. In this current review, we are aiming to shed light on strength and weakness of various BRS including the future perspective.
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