年龄相关性黄斑变性(amd)患者生活质量和认知功能的差异

Bobby Kristianto, Anak Agung Ayu Sukartini Djelantik, Ariani Andayani, Gusti Ayu Indah Triana Juliari, Anak Agung Mas Putrawati, N. M. A. Suryathi, G. R. Widiana
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摘要

前言:确定AMD患者和非AMD患者的生活质量和认知功能的差异。方法:本研究是一项观察性分析研究,一项前瞻性横断面研究,在登巴萨桑格拉RSUP综合诊所进行。结果:连续抽样共选取研究样本66人,其中AMD组33人,非AMD组33人。研究结果显示,有AMD组的平均年龄为68岁,无AMD组的平均年龄为67岁。两组均以男性居多,居住在登巴萨。大多数AMD为湿型,占60.6%。在生活质量测量方面,AMD组的所有亚量表均比非AMD组下降,总平均为27.2%,AMD组的MMSE测量的认知功能也比非AMD组下降6.8%,尽管两组的MMSE评分均在正常范围内。差异均有统计学意义(p<0.05)。结论:与非AMD组相比,AMD组患者的生活质量和认知功能明显下降,需要进一步加强治疗和筛查。
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THE DIFFERENCE OF QUALITY OF LIFE AND COGNITIVE FUNCTION BETWEEN PATIENTS WITH AND WITHOUT AGE-RELATED MACULA DEGENERATION (AMD)
Introduction: To determine the difference in the quality of life and cognitive function in patients with and without AMD. Methods: This research is an observational analytic study, a prospective cross sectional study in the polyclinic of RSUP Sanglah, Denpasar. Result: Study samples’s total are 66 people selected by consecutive sampling with 33 people in the group with AMD, and 33 people in the group without AMD. The results of the study showed the average age of the group with AMD 68 years and the group without AMD 67 years old. Most of the male sex and residence in denpasar in both groups. Most AMD with the wet type by 60.6 %. On the measurement of quality of life, it showed  decreasing in all subscale in the group with AMD compared to the group without AMD with total average 27.2 % and also decreasing in cognitive function measured by MMSE in the group of AMD compared to the group of non – AMD with 6.8%, even though the MMSE score of the groups are within normal limits. All these things stated significant differences (p<0.05) statistically. Conclusion: There are decreasing quality of life and cognitive function in AMD groupd compared to Non-AMD group which is needed more treatment and screening in the future.
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