А. С. Доронькина, И. П. Жаворонок, В. Г. Богдан, A. S. Doronkina, I. P. Zhavoronok, Vasily G. Bogdan
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Profile of pro- and anti-inflammatory cytokines during injection of fatty acid amides with ethanolamine and glycine in modeling peripheral neuropathy
The effect of fatty acid amides during the blockade of membrane orphan GPR18, GPR55 and nuclear PPARα receptors on the level of pro- and anti-inflammatory cytokines in rats with experimental peripheral neuropathy was studied. It has been proven that the anti-inflammatory action of PEA and SEA in experimental animals with neuropathy is carried out through nuclear PPARα receptors. However, PGlyA has no anti-inflamatory effects in a rat model of peripheral neuropathy.
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