蓝藻藻提取物对乳腺癌细胞株(MCF-7)的细胞毒作用及Caspase-9基因表达的变化

A. Salehzadeh, Fatemeh Sayyad Delshadpour, Ataollah Sadat Shandiz
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引用次数: 0

摘要

摘要背景与目的:乳腺癌是全球女性最常见的癌症之一。诸如治疗失败、耐药性、高昂的费用以及与此类癌症治疗相关的其他问题,吸引了许多研究人员对蓝藻菌的兴趣,因为与化学药物相比,这些微生物的副作用更少。本研究考察了振荡藻提取物对MCF7细胞株的活力及caspase-9基因表达的影响。
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Cytotoxicity Effect and Changes in the Expression of Caspase-9 Gene in Breast Cancer Cell Line (MCF-7) Treated with the Extract of Oscillatoria Cyanobacteria
Accepted: 31 Jan, 2017 Abstract Background and Objectives: Breast cancer is one of the most common cancers in women around the world. Problems, such as treatment failure, drug resistance, heavy costs, other problems associated with the treatment of this type of cancer, have attracted the interest of many researchers to cyanobacteria, since these microorganisms have fewer side-effects compared to chemical drugs. In the present research, the effect of Oscillatoria extract was investigated on the viability of MCF7 cell line as well as caspase-9 gene expression.
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