Is localized aggressive periodontitis a distinct entity? Redefinition of a unique periodontal disease

Aggressive periodontitis is a questionable disease with limited evidence supporting its incidence and mechanism. Till now, the genetic hypothesis is the most acceptable theory that supports its presence. According to literature, several unproven theories were conducted that could not provide definite explanation to its behavior. The available evidence only supported the ability to restore the destructed tissues rather than controlling the disease. The aim of the present research is trying to postulate a new hypothesis that may clarify the nature of the localized form of aggressive periodontitis.