冠状病毒;关于其生命周期和致病性的综合综述

Nighat Zia-ud-Den, A. Jamil, Muhammad Imran Kanjal, Sobia Ambreen, Zirwah Rizwan
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摘要

COVID-19是一种快速传播的新型冠状病毒,已影响150多个国家,受到全世界的关注。缺乏针对SARS-CoV-2的有效药物或疫苗使情况进一步恶化。因此,迫切需要加强研究,开发针对COVID-19的有效治疗方法和负担得起的诊断方法。在这一卫生危机时刻,科学界有责任根据重点实验方法,提供替代性、有效和负担得起的战略,为人体接种covid -19病毒感染疫苗。冠状病毒(CoV)是表面上的正向RNA病毒,含有棒状刺。它是一种不受欢迎的广泛的RNA基因组,具有无限的复制系统。在哺乳动物、鸟类、猪和鸡中,冠状病毒引起各种感染。这会引发上呼吸道的病原体,从而导致因呼吸系统疾病而死亡。在本文中,作者简要说明了最近在中东呼吸综合征冠状病毒(MERS-CoV)中发现的这种高致病性极端肺部疾病的突然发生。这是一篇关于CoVID-19感染及其在全球爆发的认识的综述文章。本文简要介绍了冠状病毒的生命周期、致病性和传播性。
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Corona Virus; A Comprehensive Overview About Its Life Cycle and Pathogenecity
COVID-19, a rapidly spreading new strain of coronavirus, has affected more than 150 countries and received worldwide attention. The lack of efficacious drugs or vaccines against SARS-CoV-2 has further worsened the situation. Thus, there is an urgent need to boost up research for the development of effective therapeutics and affordable diagnostic against COVID-19. In this time of health crisis, it is the duty of scientific research community to provide alternative, effective and affordable strategies to vaccinate human bodies against viral infections-COVID-19 based on focused experimental approaches. Corona virus (CoV) is forward RNA virus on its surface, containing stick-shaped spikes. It is an undesirable broad genome of RNA, with an indefinite replication system. In mammals, birds, pigs and chickens, corona virus cause various infections. This triggers the pathogens of the upper respiratory tract, which can lead to death due to breathing illnesses. In this article the author briefly justify sudden occurrence of this highly pathogenic extreme lung disease and recently discovered in Middle East respiratory syndrome corona virus (MERS-CoV). This is review article are awareness about the CoVID-19 infection and its out break throughout the world. In this article brief history about life cycle, pathogenecity and transmittance of corona virus given.
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