大鼠炎性疼痛模型棘上部分结构的15年探索

Gisèle Guilbaud
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引用次数: 6

摘要

重点文章总结了通过系统记录炎性疼痛大鼠模型(尾巴注射弗氏佐剂或后爪注射卡拉胶致多发关节炎大鼠)椎上中枢神经系统结构(主要是丘脑和体感皮层)的电生理数据。该研究与行为和药理学测试同时进行,以强调神经元反应的功能价值。
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15 years of explorations in some supraspinal structures in rat inflammatory pain models

The focus article summarizes electrophysiological data obtained with systematic recordings in supraspinal central nervous system structures (essentially thalamus and somatosensory cortex) of rat models of inflammatory pain (rats rendered poly-arthritic by injection of Freund's) adjuvant into the tail or injected with carrageenin into one hind-paw). The study has been performed in parallel with behavioral and pharmacological tests to emphasize the functional value of the neuronal response.

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