食用量对实验性糖尿病大鼠血清葡萄糖、甘油三酯、胆固醇、HDL、VLDL和LDL水平的影响

A. Ostovar, V. Koohi, Ali Akbar Azari Amin, Toraj Azari Amin, Arash Alizade Yekani
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引用次数: 4

摘要

糖尿病是人类的重要疾病,也是许多动物,尤其是宠物的常见疾病。本研究旨在探讨核桃对实验性糖尿病大鼠血清葡萄糖、甘油三酯、胆固醇、VLDL、LDL和HDL的影响。选取8周龄、体重200±20 g的雄性Wistar大鼠30只。然后将这些大鼠分为5组,每组6只。糖尿病治疗组和糖尿病对照组在生理盐水中皮下给予单剂量四氧嘧啶(100mg/kg BW)。倒入对照组和对照组给予生理盐水(100mg /kgBW)皮下注射。观察四氧嘧啶组糖尿病症状(多饮、多尿、高血糖、高血糖)后,我们开始以核桃颗粒等比喂养治疗组和糖尿病治疗组。各组饲喂10 d。10天结束时采集各组血液样本。糖尿病治疗组和治疗组血清甘油三酯水平与对照组比较,差异有统计学意义,但与糖尿病对照组比较,甘油三酯水平显著降低(P<0.05)。与糖尿病对照组相比,糖尿病治疗组和治疗组血清VLDL水平评价均显著降低,但与对照组相比差异无统计学意义(P<0.05)。各组血清HDL水平比较差异无统计学意义(PE©0.05)。核桃可以作为一种天然水果来预防糖尿病疾病。
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The effect of date palm consumption on the serum levels of glucose, triglyceride, cholesterol, HDL, VLDL, and LDL in rat's serum with experimental diabetes
Diabetes mellitus is an important problem in human and also it occurs in many animals, particularly in pet. This study was to evaluate walnuts effects on serum concentration of glucose, triglyceride, Cholesterol, VLDL, LDL and HDL in experimental diabetes mellitus in rat. 30 male Wistar rats with age of 8 weeks and weight of 200 ± 20 grams were selected. Then these rats were divided into five groups, 6 rats per group. Diabetic treatment group and diabetic control group received subcutaneous a single dose of Alloxan (100mg/kg BW) in saline solution. Pour control group and control group received subcutaneous saline normal (100 mg/kgBW). After observed diabetes symptoms (Polydipsia, Polyuria,Glucosuria and Hyperglycemia) in groups that were received Alloxan, we have initiated to feeding treatment group and diabetic treatment group in the ratio of equal with walnuts and pellet. These groups were fed for 10 days. Blood samples collected from whole groups at the end of 10day. Evaluation of the serum levels of triglyceride revealed statistically significant differences in diabetic treatment group and treatment group with control group, but decreased significantly compared to the diabetic control group (P<0.05).Evaluation of the serum Levels of VLDL decreased significantly in diabetic treatment group and treatment group compared to the diabetic control group, but did not reveal statistically difference compared to the control group (P<0.05). Evaluation of the serum levels of HDL did not reveal statistically significant difference between groups (PEƒ0.05). The walnut can be used as a natural fruit for prevent than diabetes mellitus disorders.
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