纳米材料在导管相关医院感染中的作用

Sujayita Mazumder, Gopa Roy Biswas, Anamika Saha
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引用次数: 0

摘要

在当前的医疗环境中,医院感染被认为是最危及生命的感染之一。住院病人暴露于各种来源的污染物,包括医务人员和其他病人。细菌相关生物膜感染在中央静脉相关血液感染、导尿管相关尿路感染、手术部位感染和呼吸机相关呼吸系统中扩散。根据世卫组织的报告,所有住院患者中有近15%患有这种感染。留置导尿管患者发生尿路感染的风险较高,因为生物膜形成细菌可以直接进入泌尿系统。金属基纳米颗粒在防止生物膜破坏方面比传统抗生素更有利。工程定制纳米颗粒的创造可能标志着有效治疗由留置导管上生物膜生长引起的医院感染的新时代。医院感染,医疗保健相关感染,导管相关感染,工程定制纳米颗粒,生物膜表面。
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Effect of nanomaterials in catheter related nosocomial infection
In the current healthcare environment, nosocomial infection is regarded as one of the most life-threatening infections. Hospitalized patients are exposed to contaminants from a range of sources, including medical staff and other sick people. Bacteria associated biofilm infection spread in central line associated blood infections, catheter-associated urinary tract infection, surgical site infection and ventilator-associated respiratory system. According to WHO reports, nearly 15% of all hospitalized patients suffer from this infection. Patients with indwelling urinary catheters have a higher risk of developing urinary tract infections because biofilm formation bacteria can enter the urinary system directly. Metal based nanoparticles is the most advantageous in prevention of biofilm disruption rather than conventional antibiotics. The creation of engineering tailored nanoparticles may signal a new era in the efficient treatment of nosocomial infection caused by the growth of biofilm over indwelling catheters. Nosocomial infections, Healthcare associated infection, Catheter associated infections, engineering tailored nanoparticles, Biofilm Surface.
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