Anshuman C. Desai, P. Low, M. Camilleri, W. Singer, D. Burton, S. Chakraborty, A. Bharucha
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Utility of the plasma pancreatic polypeptide response to modified sham feeding in diabetic gastroenteropathy and non‐ulcer dyspepsia
The relationship between cardiovascular and gastrointestinal (ie, plasma pancreatic polypeptide [PP] response to modified sham feeding [MSF]) indices of vagal function is unclear. Hyperglycemia inhibits PP secretion via vagally mediated mechanisms. Our aims were to (a) compare the PP response, (b) its relationship with glycemia, and (c) the relationship between PP response to MSF, gastric emptying (GE) of solids, and symptoms during GE study in healthy controls, patients with diabetic gastroenteropathy (DM), and non‐ulcer dyspepsia (NUD).
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