{"title":"胸部CT成像作为检测患者COVID-19感染严重程度的重要工具及其与RT-PCR的相关性","authors":"Anand Sorikunte Huchappa, Vineetha Kolar Venkataravanappa, Kambathanahalli Paramashivaiah Suresh Babu","doi":"10.18231/j.ijfcm.2022.022","DOIUrl":null,"url":null,"abstract":"Since its emergence in 2019, RT-PCR is a standard test for the detection of SARS-CoV-2 viral infection (COVID-19). Chest-CT scans are the preferred most common routine test to determine the spread and severity of the disease. The present study aims to demonstrate a comparative analysis of chest CT and RT-PCR as diagnostic tests for COVID-19 detection.In this prospective single-center study a total of 979 patients (Male= 614, female= 365) from Tumkur, Karnataka (India) who were suspected of novel coronavirus infection underwent both chest CT and RT-PCR assay.Patients with positive RT-PCR and abnormalities in chest CT images were identified. The patients with negative RT-PCR and positive chest-CT images and vice versa were screened for the accuracy of both techniques. Out of 979 patients, 674 (68.85%) patients had positive CT index scores, whereas 613 (62.61%) patients had positive RT-PCR tests. Most of the patients (47%) were from the age group 36-55 years with most of the population having hypertension (8.27%) and diabetes (6.44%). Corad score revealed 88.36% of patients (865) with high infection. In patients with negative RT-PCR reports (31.15%; 305/979), a positive CT index was observed in 7.25% of patients indicating higher sensitivity to this technique. A chest CT scan is superior in sensitivity for the detection of COVID-19 than that of RT-PCR. The CT scan can be used asa confirmatory diagnostic test for COVID-19 suspects whose RT-PCR test results are negative.","PeriodicalId":13276,"journal":{"name":"Indian journal of forensic and community medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Chest CT imaging as an essential tool to detect the severity of COVID-19 infection in patients and its correlation with RT-PCR\",\"authors\":\"Anand Sorikunte Huchappa, Vineetha Kolar Venkataravanappa, Kambathanahalli Paramashivaiah Suresh Babu\",\"doi\":\"10.18231/j.ijfcm.2022.022\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Since its emergence in 2019, RT-PCR is a standard test for the detection of SARS-CoV-2 viral infection (COVID-19). Chest-CT scans are the preferred most common routine test to determine the spread and severity of the disease. The present study aims to demonstrate a comparative analysis of chest CT and RT-PCR as diagnostic tests for COVID-19 detection.In this prospective single-center study a total of 979 patients (Male= 614, female= 365) from Tumkur, Karnataka (India) who were suspected of novel coronavirus infection underwent both chest CT and RT-PCR assay.Patients with positive RT-PCR and abnormalities in chest CT images were identified. The patients with negative RT-PCR and positive chest-CT images and vice versa were screened for the accuracy of both techniques. Out of 979 patients, 674 (68.85%) patients had positive CT index scores, whereas 613 (62.61%) patients had positive RT-PCR tests. Most of the patients (47%) were from the age group 36-55 years with most of the population having hypertension (8.27%) and diabetes (6.44%). Corad score revealed 88.36% of patients (865) with high infection. In patients with negative RT-PCR reports (31.15%; 305/979), a positive CT index was observed in 7.25% of patients indicating higher sensitivity to this technique. A chest CT scan is superior in sensitivity for the detection of COVID-19 than that of RT-PCR. The CT scan can be used asa confirmatory diagnostic test for COVID-19 suspects whose RT-PCR test results are negative.\",\"PeriodicalId\":13276,\"journal\":{\"name\":\"Indian journal of forensic and community medicine\",\"volume\":\"12 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian journal of forensic and community medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18231/j.ijfcm.2022.022\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian journal of forensic and community medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.ijfcm.2022.022","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Chest CT imaging as an essential tool to detect the severity of COVID-19 infection in patients and its correlation with RT-PCR
Since its emergence in 2019, RT-PCR is a standard test for the detection of SARS-CoV-2 viral infection (COVID-19). Chest-CT scans are the preferred most common routine test to determine the spread and severity of the disease. The present study aims to demonstrate a comparative analysis of chest CT and RT-PCR as diagnostic tests for COVID-19 detection.In this prospective single-center study a total of 979 patients (Male= 614, female= 365) from Tumkur, Karnataka (India) who were suspected of novel coronavirus infection underwent both chest CT and RT-PCR assay.Patients with positive RT-PCR and abnormalities in chest CT images were identified. The patients with negative RT-PCR and positive chest-CT images and vice versa were screened for the accuracy of both techniques. Out of 979 patients, 674 (68.85%) patients had positive CT index scores, whereas 613 (62.61%) patients had positive RT-PCR tests. Most of the patients (47%) were from the age group 36-55 years with most of the population having hypertension (8.27%) and diabetes (6.44%). Corad score revealed 88.36% of patients (865) with high infection. In patients with negative RT-PCR reports (31.15%; 305/979), a positive CT index was observed in 7.25% of patients indicating higher sensitivity to this technique. A chest CT scan is superior in sensitivity for the detection of COVID-19 than that of RT-PCR. The CT scan can be used asa confirmatory diagnostic test for COVID-19 suspects whose RT-PCR test results are negative.