Maria Bekker-Nielsen Dunbar, Felix Hofmann, Leonhard Held, the SUSPend modelling consortium
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Assessing the effect of school closures on the spread of COVID-19 in Zurich
The effect of school closure on the spread of COVID‐19 has been discussed intensively in the literature and the news. To capture the interdependencies between children and adults, we consider daily age‐stratified incidence data and contact patterns between age groups which change over time to reflect social distancing policy indicators. We fit a multivariate time‐series endemic–epidemic model to such data from the Canton of Zurich, Switzerland and use the model to predict the age‐specific incidence in a counterfactual approach (with and without school closures). The results indicate a 17% median increase of incidence in the youngest age group (0–14 year olds), whereas the relative increase in the other age groups drops to values between 2% and 3%. We argue that our approach is more informative to policy makers than summarising the effect of school closures with time‐dependent effective reproduction numbers, which are difficult to estimate due to the sparsity of incidence counts within the relevant age groups.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.