局部治疗的免疫反应

A. Smolock, S. White
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引用次数: 0

摘要

对癌症的免疫反应是一个持续关注的领域,也是新的全身性药物的焦点。肝脏定向治疗一直是肝脏原发性和转移性疾病的标准治疗方法。越来越多的人认识到这些疗法可能影响更广泛的全身反应和免疫激活。本文回顾了支持这一现象的临床和转化数据。本文综述了肝脏靶向治疗的免疫反应的研究结果和潜在影响。
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Immune Response to Locoregional Therapy
Abstract The immune response to cancer is an ongoing area of interest and is the focus of newer systemic agents. Liver-directed therapy has been the standard treatment for primary and metastatic disease limited to the liver. It is increasingly being recognized that these therapies may influence a broader systemic response and immune activation. The clinical and translational data supporting this phenomenon are reviewed herein. The findings and potential impact of the immune response to liver-directed therapies are summarized in this article.
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