慢性肾功能衰竭的贫血和左心室肥厚

Gergana V. Todorova, A. Akisheva, M. Stoimenova
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摘要

慢性肾衰竭(CRF)综合征显著改变患者的生活质量。贫血、高血压和心血管疾病是CRF的常见并发症。本研究旨在确定CRF患者动脉高血压(AH)、贫血和左心室肥厚(LVH)的发生率,并分析三者之间的关系。该研究包括2008-2020年期间在普列文大学医院“Dr. G. Stranski”肾内科和透析诊所接受治疗的212例CRF患者。AH占CRF患者的88.2%。AH的发生率与透析前患者的发生率(88.6%)和透析患者的发生率(87.9%)相当。94.3%的CRF患者诊断为LVH。透析前LVH发生率为94.3%,透析患者LVH发生率为-94.4%。高血压患者和正常患者LVH的发生率是相似的。CRF患者中贫血发生率为86.3%。94.4%的透析患者和78.1%的透析前患者存在贫血。差异有统计学意义(p <0.05)。贫血和AH之间没有相关性,AH和LVH之间也没有相关性。LVH与慢性肾功能衰竭和透析治疗的持续时间有显著的相关性。
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Anemia and Left Ventricular Hypertrophy in Chronic Renal Failure
Summary Chronic renal failure (CRF) syndrome significantly alters patients’ quality of life. Anaemia, hypertension, and cardiovascular diseases are common complications of CRF. The study aimed to determine the incidence of arterial hypertension (AH), anaemia, and left ventricular hypertrophy (LVH) in patients with CRF and to analyze the relationship between them. The study included 212 patients with CRF, treated at the Clinic of Nephrology and Dialysis at the University Hospital “Dr. G. Stranski,” Pleven, during 2008-2020. The AH accounted for 88.2% of the patients with CRF. The incidence of AH is comparable to that in patients in the predialysis period – 88.6% and among patients on dialysis – 87.9%. LVH was diagnosed in 94.3% of patients with CRF. The incidence of LVH in the predialysis period was 94.3%, and among dialysis patients -94.4%. The incidence of LVH among hypertensive and normotensive patients was comparable. The incidence of anaemia among patients with CRF was 86.3%. Anaemia was present in 94.4% of the patients on dialysis and in 78.1% of the patients in the predialysis period. The difference was significant (p <0.05). There was no correlation between anaemia and AH, nor between AH and LVH. A significant dependence of LVH on the duration of chronic renal failure and dialysis treatment was established.
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