伊朗感染COVID-19的母亲健康分娩:过程和保护

Hamideh Abbaspour Kasgary, Parisa Moradimajd, Hamidreza Samaei, L. Davoodi
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摘要

背景:2019年12月下旬,一种新型冠状病毒(SARS-CoV-2)引起的肺炎在中国湖北省武汉市出现。这种病毒在世界范围内迅速传播,感染了包括伊朗在内的195个国家和地区。截至2020年3月22日,该病毒已影响全球4万多人,造成1.9万多人死亡。孕妇是易受病毒感染的群体,因为在怀孕期间会发生部分免疫抑制。因此,COVID-19疫情可能会引起全球对其对孕妇和胎儿后果的日益关注。目的:在本病例研究中,我们报告了一名孕妇在确诊COVID-19后分娩的情况。方法:我们报告了一名44岁(孕32周)感染COVID-19的孕妇,她生下了一名健康的婴儿,没有COVID-19的证据。我们没有观察到任何更差的临床结果,如产妇死亡率、死产、自然流产和早产。结果:早产女1例,体重2500 g, Apgar评分分别为5分钟、10分钟、9分钟和10分钟。早产儿头位正常,无黄疸巩膜,心音正常,无杂音,肺通气正常。结论:病毒性肺炎可能在妊娠期发生严重的生理和免疫变化,由细胞免疫向体液免疫转变。COVID-19母婴垂直传播、对母亲和新生儿的短期和长期不良影响仍不清楚,也存在争议。
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Healthy Baby Delivery of a COVID-19 Infected Mother in Iran: Process and Protection
Background: In late December 2019, a kind of pneumonia caused by a novel coronavirus (SARS-CoV-2) emerged in Wuhan, Hubei Province, China. This virus rapidly spread worldwide and infected 195 countries and territories, including Iran. By March 22, 2020, the virus had affected more than 40000 people worldwide and caused more than 19000 deaths. Pregnant women are a vulnerable group to viral infections because partial immune suppression occurs during pregnancy. Therefore, the COVID-19 epidemic may cause a rising global concern about its consequences for pregnant women and fetuses. Objectives:In this case study, we report the delivery of a pregnant woman after her COVID-19 confirmation. Methods: We report a 44-year-old pregnant woman (32 weeks gestation) with COVID-19 who gave birth to a healthy baby with no evidence of COVID-19. We did not observe any worse clinical outcomes, such as maternal mortality, stillbirth, spontaneous abortion, and preterm delivery. Results: A preterm baby girl with 2500 g weight and Apgar scores at 5 minutes and 10 minutes were 9 and 10 was delivered. The preterm baby was normocephalic, had no icteric sclera, and the heart sounded normal without murmurs, Lung ventilation was normal. Conclusion: Viral pneumonia may severely be presented in pregnancy because of physiological and immunological changes and shift from cell-mediated to humoral-mediated immunity during the pregnancy period. Vertical transmission of COVID-19 from mother to child, shortterm and long-term adverse effects on mother and newborn are still unclear and controversial.
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