滨海边疆区青少年结核病筛查和早期诊断

L. N. Motanova, P. E. Kalashnikov
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摘要

的目标。确定在滨海边疆区组织青少年结核病感染筛查和早期诊断方面的肺结核服务目标。材料和方法。对滨海边疆区结核病诊疗所1994-2021年流行病学监测数据进行分析。评估了结核病发病率、新诊断病例的临床结构、结核病进程的各个阶段以及细菌排泄的存在。在0.95的水平上,在可选假设下检验相等份额的统计假设。医疗机构联合形成统一的医疗网络,采用重组结核过敏原(TBA)进行大规模免疫诊断,提高了青少年结核病筛查效率。结核病发病率的下降和新诊断病例的临床结构的改善证实了这一点。在青少年新诊断病例的临床结构中继发结核形式的流行证明了每年进行x线检查的重要性。青少年应优先进行年度RTA检测和6个月1次胸部x线检查。青少年结核病仍然是一个严重的生理问题。青少年结核病筛查和早期发现的有效系统应包括大规模免疫诊断和间隔6个月的胸部x线检查。
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Tuberculosis screening and early diagnostics in adolescents in Primorsky Krai
Aim. To define the objectives of phthisiatric service with respect to organizing screening for tuberculosis infection (TB) and early diagnostics among adolescents in Primorsky Krai.Material and Methods. The data of epidemiological monitoring conducted by the Primorsky Regional TB Dispensary in 1994–2021 were analyzed. The TB incidence, clinical structure of newly-diagnosed cases, phases of the tuberculosis process, as well as the presence of bacterial excretion were assessed. At a level of 0.95, the statistical hypothesis of equal shares was tested under an alternative hypothesis.Results. The implementation of mass immunodiagnostics using the recombinant tuberculosis allergen (TBA) by medical organizations, which are joint into a unified medical network, improves screening efficiency of TB among adolescents. This is confirmed by a decreased TB incidence rate and improved clinical structure of newly-diagnosed cases. The prevalence of secondary TB forms in the clinical structure of newly-diagnosed cases in adolescents justifies the importance of annual fluorographic examination. Annual RTA testing and fluorographic examination of the chest in adolescents once every six months should be a priority anti-tuberculosis measure.Conclusions. TB in adolescents remains to be a serious phthisiological problem. An effective system of screening and early detection of TB in adolescents should include mass immunodiagnostics and, with an interval of six months, fluorographic examination of the chest.
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