MicroRNA表达分类用于人类疾病预测

Ines Slimene, Imen Messaoudi, A. Oueslati, Z. Lachiri
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引用次数: 0

摘要

近年来的研究表明,microRNA在人类疾病规范中起着重要的作用。miRNA表达的研究有助于加快疾病的诊断和预测治疗。然而,从微小rna表达(如RPM)来实验鉴定疾病存在困难。目前,我们还没有足够的生物信息学算法来预测miRNA与疾病之间的关系。在这里,我们提出了一种基于机器学习的方法,基于miRNA表达来区分患者和正常人。在本文中,我们比较了不同的机器学习算法,如SVM, KNN和逻辑回归,以预测miRNAs RPM值的感染基因。
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MicroRNA expression classification for human disease prediction
Recent research has shown that microRNA plays an important role in human disease specification. Study of miRNA expression helps to accelerate the diagnosis of diseases and to anticipate treatment. However experimental identification of diseases from microRNA expression such as RPM poses difficulties. Nowadays, we haven't enough bioinformatics algorithm to predict the association between miRNA and diseases. Herein, we present a machine learning based approach for distinguishing patient from normal person based on miRNA expression. In this paper, we compare different machine learning algorithms such as SVM, KNN and logistic regression to predict infected gene from miRNAs RPM values.
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