噬菌体抗脓性炎症(葡萄球菌,链球菌)病理

T. Gabisonia, I. Giorgadze, N. Topuria, L. Chanishvili, M. Nadiradze, N. Chakhunashvili, T. Katamadze, M. Loladze, N. Tamarashvili, M. AlibegaSvili, Kal, T. arishvili, T. Eliava
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引用次数: 2

摘要

在传染病和非传染病诊所预防和治疗传染病的问题是实际公共卫生的优先事项之一。噬菌体制剂的应用,作为抗葡萄球菌和链球菌感染的抗微生物中预防性补救措施,似乎是抗生素和磺胺制剂的替代品。流行致病菌菌株对抗生素敏感性降低的明显趋势,也是由抗生素的不合理使用引起的,进一步证实了我们创造一种新的噬菌体制剂的决定。在已有研究的基础上,制备了Fersis的新变种,这是一种活性的多价噬菌体制剂,由抗引起口腔传染病的葡萄球菌(金黄色葡萄球菌、表皮葡萄球菌)和链球菌(化脓性葡萄球菌、葡萄球菌、血源性葡萄球菌、唾液链球菌、无乳链球菌)的噬菌体组成。
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Fersis-Phage against Purulent-Inflammatory (Staphylococcal, Streptococcal) Pathologies
The problem of prevention and treatment of infectious diseases in infectious and non-infectious clinics is one of the priorities in practical public health. The application of phage preparations, as antimicrobial medioprophylactic remedies against staphylo- and streptococcal infections seems to be an alternative to antibiotics and sulfonamide preparations. Pronounced tendency of circulating pathogenic bacterial strains towards reducing sensitivity to antibiotics, also caused by irrational use of the latter, further confirmed our decision to create a new phage preparation. Based on the conducted studies the new variant of Fersis, an active, multivalent phage preparation, consisting phages against staphylococci (S. aureus, S. epidermidis) and streptococci (S. pyogenes, S. viridians, S. sanguis, S. salivarius, S. agalacticae) causing oral cavity infectious diseases, has been prepared.
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