提高固体剂型生物利用度的新方法

Apurva Vunnava, N. S. Kumar, Kunal Kumar Jogdande
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引用次数: 1

摘要

自古以来一直使用的固体剂型在给药系统方面进行了修改。由于固体剂型有许多不良反应,最近发展了先进的技术来尽量减少不良反应。这些技术是用基质和聚合物胶束封装药物。这两种技术在近代有很好的重要用途。它们优化了药物的生物利用度、药代动力学和药效学特性。他们的给药系统的进一步发展是在给药系统中应用纳米技术。纳米技术在给药中的应用将进一步减少药物的不良反应。
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Novel Approaches to Enhance, Bioavailability of Solid Dosage Forms
Solid dosage forms, which were being used since ancient days, have been made modifications in terms of their drug delivery systems. As there are many adverse effects caused by solid dosage forms, recent advanced techniques were developed to minimize the adverse effects. These techniques are encapsulating the drug with matrix, and polymer micelles. These two techniques have a good significant use in the recent era. They optimize the bioavailability, pharmacokinetic and Pharmodynamic properties of the drug. Further advance in their drug delivery system is by applying nanotechnology in their drug delivery system. Applications of Nanotechnology in drug delivery would further minimize the adverse reaction.
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