孟加拉国通济工业区生活饮用水质量评价及其对健康大鼠的毒理学影响

Sauda Binte Sunjida, S. Yesmine, Imon Rahman, R. Islam
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引用次数: 7

摘要

快速的工业化和不断恶化的水质对工业众多地区居民的健康造成了灾难性的影响。本研究简要反映了工业化对水资源的毒理学效应,以及受污染的生活饮用水对发展中国家工业化地区动物模型的药理效应。本研究所得结果显示,工业用水中某些重金属浓度偏高,超过了世界卫生组织水准则所允许的最高限量,可能导致血液成分异常,严重影响肾脏和肝脏等重要器官。随后,饮水的受试大鼠模型各器官均出现明显异常。因此,本研究结果可用于通过扩大采样区域来开展长期研究,并进一步阐明人类暴露于工业地区污染水的分子机制和公共卫生影响。
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Assessing the Quality of Household and Drinking Water in Tongi Industrial Zone of Bangladesh and Its Toxicological Impact on Healthy Sprague Dawley Rats
Rapid industrialization, deteriorating the quality of water leads towards disastrous health effects among the inhabitants of the areas with numerous industries. This study is a brief reflection of the toxicological effects of industrialization on water resources, as well as the pharmacological effects of contaminated household and drinking water on animal model of an industrialized area in a developing country. The obtained results of this study showed high concentration of some heavy metals in the water used in industrial area, than the maximum permissible limit that can be present in water according to the WHO guidelines of water which might cause anomaly in blood composition, severe effect on vital organs such as kidneys and livers. Successively, significant abnormalities were observed in the organs of the tested rat models drinking the water. Therefore, the findings of this study can be used to implement the long term study by broadening the sampling areas and to further elucidate the molecular mechanisms and public health impact associated with human exposure to water contaminated in the industrial areas.
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