念珠菌-一种新出现和再出现的病原体

R. Swaminathan, N. Kamath
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引用次数: 0

摘要

念珠菌含有广泛的生物体,超过17种不同的念珠菌与人类感染有关。新的物种正在出现,白色念珠菌和其他物种正在重新出现。分离的菌株显示出增加的抗真菌耐药性,这需要新的抗真菌药物。念珠菌可引起广泛的真菌病,包括侵袭性念珠菌病,它可以是深度的,广泛的,并且非常痛苦。大多数情况下,它通过内源性念珠菌血症传播。它们附着在宿主组织和医疗设备上,形成生物膜,并释放分解蛋白质的酶。常规技术和分子技术使实验室诊断念珠菌变得容易。然而,念珠菌感染在免疫功能低下和住院患者中更为常见。
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Candida-An emerging and re-emerging pathogen
Candida contains a wide range of organisms, and more than 17 different Candida species have been linked to human infections. Newer species are emerging and Candida albicans and other Species are re-emerging. Isolated strains showing increased antifungal resistance, which necessitates the need for new antifungal drugs. Candida Spp can cause a wide range of mycoses, including invasive candidiasis, which can be deep, widespread, and extremely painful. The majority of the time, it spreads by endogenous Candidaemia. They adhere to host tissues and medical equipment, form biofilms, and release enzymes that break down proteins. Conventional techniques and molecular techniques have made laboratory diagnosis of Candida easy. However, Candida infections are more common in immunocmpromised and hospitalised patients.
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