抗癌药物组合,从不同途径的研究

D. Lu
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引用次数: 14

摘要

大多数癌症治疗基于多种基因改变和分子异常的单一抗癌药物很少有效。抗癌联合用药企业需要从经验型企业向科技型企业转变。这篇社论通过数学查询提供了药物联合治疗的背景知识。可能的未来景观和目前的癌症药物联合治疗的缺点进行了讨论和推测。
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Anticancer Drug Combinations, Studies from Different Pathways
Most cancer therapies are seldom effective by single anticancer drug based on multiple genetic alterations and molecular abnormalities. Anticancer drug combination utilities need to transform from empirical to science-guided enterprises. This editorial offers the background knowledge of drug combination therapies by mathematical enquiry. Possible future landscapes and drawbacks of current cancer drug combinative therapy are addressed and speculated.
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