运动神经元疾病的治疗与管理综述

Shweta S. Bobade, Komal D. Pol, Mahesh S. Mali, Pradnya N. Jagtap, Sumit K. Musale
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摘要

运动神经元病(MND)是一种预后差、致残严重的破坏性神经退行性疾病。许多潜在的外部危险因素被认为是MND病因学中基因-环境相互作用的一部分。这一结果也得到了目前关于MND的细胞和遗传起源的假设的支持。一种加重额颞叶痴呆的运动神经病变称为MND (FTD)。额叶和颞叶新皮质萎缩导致FTD患者严重的人格改变、不恰当的社会行为和执行困难。运动神经元疾病可引起球麻痹和肢体肌萎缩等症状。额叶执行功能缺陷见于未被视为痴呆的MND/肌萎缩侧索硬化症(ALS)患者。此外,MRI显示额叶异常。根据阿育吠陀的说法,精神病是由Vata Dosha引起的。瓦塔斯负责神经系统的自主、外周和中枢功能。它监督大脑的认知和神经过程。这篇文章给出了关于阿育吠陀在治疗MND中的信息,Panchakarma治疗MND,各种草药和草药配方,如Ashwagndha, Brahmi, Gotu kola, Shilajit, Kapakacchu, VrihatVatchintamani Ras, Medhyachurna用于治疗和管理MND。
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A Review on Ayurved in the Treatment and Management of Motor Neuron Disease
Motor neuron disease (MND) is a devastating neurodegenerative disease with a poor prognosis and severe disability. Many potential external risk factors have been proposed as part of a gene-environment interaction in the etiology of MND. This result is also supported by current hypotheses concerning the cellular and genetic origins of MND. A motor neuronopathy that exacerbate frontotemporal dementia is known as MND (FTD). Frontal and temporal neocortical atrophy induce severe personality changes, inappropriate social conduct, and executive difficulties in people with FTD. Motor neuron disease causes symptoms such as bulbar palsy and limb amyotrophy. Frontal executive function deficits are seen in MND/amyotrophic lateral sclerosis (ALS) patients who are not considered demented. Furthermore, MRI has revealed anomalies in the frontal lobe. MND, according to Ayurveda, are caused by Vata Dosha. Vatais in charge of the nervous system's autonomic, peripheral, and central functions. It oversees the brain's cognitive and neurological processes. This article gives the information about the Ayurveda in management of MND, Panchakarma treatments for MND, various herbs and herbal formulations like Ashwagndha, Brahmi, Gotu kola, Shilajit, Kapakacchu, VrihatVatchintamani Ras, Medhyachurna used in the treatment and management of MND.
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