IgA抗组织转谷氨酰胺酶假阴性

N. Boutrid, H. Rahmoune, M. Amrane
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引用次数: 0

摘要

随着对谷蛋白相关自身免疫知识的不断扩展,以血清学为基础的分步诊断乳糜泻的方法可能会因实验室技术而产生误导。我们报告了一个罕见的病例,最初的抗谷氨酰胺酶IgA抗体假阴性,而CD是通过抗谷氨酰胺酶IgG和随后的十二指肠活检证实的。
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False-negative IgA Anti-tissue Transglutaminase
The expanding knowledge about gluten-related autoimmunity led to a serology-based step-wised approach to diagnose celiac disease that might be misleading due to laboratory techniques. We present a rare case associating initial false-negative anti-transglutaminase IgA antibodies while CD was confirmed by IgG anti-transglutaminase and subsequent duodenal biopsy.
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