干细胞研究的综合指南

Vinita Thakur
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摘要

干细胞是未分化的细胞,分为两类:a)胚胎发育的囊胚期形成的胚胎干细胞和b)成人的干细胞。胚胎干细胞来源于4-5天大的处于发育阶段的囊胚期的人类胚胎。成体干细胞存在于胚胎发育后的全身,存在于不同类型的组织中。成人骨髓和脂肪中含有干细胞以及其他组织。除了这两种类型之外,还有胚胎生殖细胞,这些细胞是从发育后期的胎儿性腺脊区收集的。成体干细胞是生物体中新鲜的细胞来源,它们替代了像血液和其他结缔组织一样需要定期替换的细胞。干细胞技术在再生医学领域正迅速发展。根据Patil AM的说法,干细胞研究为退行性疾病、损伤和其他疾病提供了一种新的可行的治疗选择。干细胞被称为主细胞,能够生长成200多种细胞类型[6,7]。根据它们的分裂和分化能力,它们可以是全能性、多能性或多能性bbb。
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A comprehensive guide for the stem cell research
Stem cells are undifferentiated cells classified into two groups, a) stem cells from embryos formed during the blastocyst phase of an embryological development and b) stem cells of an adult. Embryonic stem cells are derived from a 4-5 day old human embryo that is in the blastocyst phase of a development [1]. Adult stem cells exist throughout the body after embryonic development and are found inside of different types of tissues. Adult bone marrow and fat have stem cells along with other tissues [2]. Apart from these two types there is also embryonic germ cells which are collected from the fetus later in developmental process from gonadal ridge [3]. Adult stem cell serve as fresh source of cells in living organism They replace the cells that need to be replaced on regular basis like blood and other connective tissue [4]. Stem cell technology is rapidly growing in the field of regenerative medicine [5]. According to Patil AM, stem cell research has offered a new viable therapeutic option for degenerative diseases, injuries and other diseased condition. Stem cells are called as master cells with ability to grow into more than 200 cell types [6,7]. Based on their capacity to divide and differentiate they may be totipotent, pluripotent or multipotent [5].
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