Analysis of the corneal spherical aberration in patients with primary angle-closure glaucoma with cataract

Objective To analyze the distribution and related factors of the spherical aberration in patients with primary angle-closure glaucoma and cataract. Methods Retrospective series of case study. The data of 154 eyes of 120 patients of primary angle-closure glaucoma with cataract from Nov. 2018 to Mar. 2019 in this hospital were analyzed. Pentacam HR anterior segment analyzer (Oculus, Germany) was used to measure and analyse datas. Results The average age of patients was (68.00±9.95) years, ranged from 33 to 85 years. The average spherical aberration was (0.35±0.16) μm, ranged from -0.35 μm to 0.76 μm. A positive correlation was found between spherical aberration and age(r=0.287, P=0.000), spherical aberration and mean corneal refractive power(r= 0.170, P=0.035). A negative correlation was found between spherical aberration and corneal refractive power of posterior surface(r=-0.164, P=0.042). There were no correlation between spherical aberration and corneal diameter, corneal thickness, corneal volume and axis length(r=-0.034, -0.149, -0.126, -0.123, P=0.681, 0.066, 0.119, 0.134). With residual spherical aberration(0.1±0.05)μm as the target, 90 eyes (58.4%) were corrected by different aspheric IOLs(0, -0.20 μm, -0.27 μm). Conclusion Corneal spherical aberration in patients with primary angle-closure glaucoma and cataract is larger than that reported in other populations(+ 0.27 μm), and with larger fluctuation range. A suitable IOL should be selected according to the preoperative comprehensive evaluation of personalized spherical aberrations, pupil, visual field and the injury of the optic nerve. Key words: Glaucoma; Cataract; Aberration, spheric, corneal; Lens, intraocular, aspheric