含有β-内酰胺基团的生物活性表面活性剂:合成及其性质

L. Molina, A. Perani, M. Infante, M. Manresa, M. Maugras, S. Achilefu, M. Stébé, C. Selve
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引用次数: 7

摘要

用P(NMe2) 3-CCl4选择性活化3-羟基-2-羟甲基-2-甲基丙酰胺,并随后进行分子内环化,产生具有表面和抗生素活性的β-内酰胺衍生物。
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Bioactive surfactants containing a β-lactam group: synthesis and properties
Selective activation of 3-hydroxy-2-hydroxymethyl-2-methyl propanamide with P(NMe2)3–CCl4, and subsequent intramolecular cyclisation yields β-lactam derivatives that have both surface and antibiotic activity.
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