环丙沙星对T2DM患者尿路感染细菌的敏感性描述

Muhammad Ibnu Nazari
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引用次数: 0

摘要

糖尿病是一种慢性代谢性疾病,其特征是由于胰腺缺乏胰岛素产生或身体无法使用产生的胰岛素或两者兼而有之而导致高血糖状态。不受控制的高血糖会抑制免疫系统,使身体容易受到感染,尤其是尿路感染(uti)。尿路感染治疗的主要选择是抗生素治疗,最常用的一种是氟喹诺酮类药物中的环丙沙星。本研究采用描述性方法和流行病学研究。采用琼脂扩散法进行抗生素敏感性试验。样本数量采用总抽样法。对22株菌株进行环丙沙星敏感性试验。大肠杆菌对环丙沙星敏感66.67%,中等耐药16.67%。铜绿假单胞菌60%敏感,40%中间。产气肠杆菌敏感66.67%,中间33.33%。志贺氏菌100%敏感,克雷伯氏菌100%耐药。本研究结论表明环丙沙星是治疗尿路感染的有效经验疗法。
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Description Of Ciprofloxacin Sensitivity On Bacteria Causing UTI In T2DM Patients
Diabetes mellitus is a chronic metabolic disease characterized by a state of hyperglycemia due to a lack of insulin production by the pancreas or the body's inability to use the insulin produced or both. Uncontrolled hyperglycemia can suppress the immune system and making the body vulnerable to infection, especially urinary tract infections (UTIs). The main choice in UTI treatment is antibiotic therapy, one of the most frequently used is ciprofloxacin from the fluoroquinolone group.The research design used was descriptive method with prevalence studies. The research was done using antibiotic sensitivity tests with agar diffusion methods. The number of samples were taken using total sampling method.The results of ciprofloxacin sensitivity test were obtained as many as 22 isolates. Escherichia coli bacteria are sensitive to ciprofloxacin at 66.67%, intermediate and resistant 16.67% respectively. Pseudomonas aeruginosa are 60% sensitive and 40% intermediate. Enterobacter aerogenes are 66,67% sensitive and 33,33% intermediate. Shigella spp. are 100% sensitive, and Klebsiella spp. 100% resistant.The conclusion from the study showed that ciprofloxacin are an effective empirical therapy for UTI.
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