塞沧醇提物与丁香芽油复合透明固体皂的配方及对皮肤病细菌的抗菌活性

R. Aryani, Y. Lukmayani, S. Hazar
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引用次数: 1

摘要

杉木醇提物和丁香芽油对金黄色葡萄球菌、痤疮丙酸杆菌、铜绿假单胞菌均有抗菌作用。透明沐浴皂的配方为身体提供了额外的保护。本研究配制肥皂,并测定其对金黄色葡萄球菌、痤疮丙酸杆菌和铜绿假单胞菌的抑菌活性。采用热法制备皂液,并用琼脂扩散法测定皂液的抑菌活性。配方F0(作为基料)、F1(3%丁香芽油)和F2(3%丁香芽油和0.5%皂化木乙醇提取物的组合)具有良好的外观和质量,包括pH值、泡沫稳定性、游离碱、不皂化脂肪和矿物油含量。肥皂的含水量>15%。皂液对金黄色葡萄球菌、痤疮假单胞菌和铜绿假单胞菌的抑制直径值(F0、F1和F2)均为中~强。根据90秒的接触时间测试,F0不能杀死细菌;F1能杀灭金黄色葡萄球菌、痤疮丙酸杆菌和铜绿假单胞菌;F2在90秒内杀死金黄色葡萄球菌,在60秒内杀死痤疮丙酸杆菌和铜绿假单胞菌。关键词:香皂,丁香芽油,香醇,抗菌
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Formulation and Antibacterial Activity of Transparent Solid Soap Combination of Secang Ethanolic Extract and Clove Bud Oil Against Skin Disease Bacteria
Secang wood ethanolic extract and clove bud oil have antibacterial properties against Staphylococcus aureus, Propionibacterium acnes, and Pseudomonas aeruginosa. The formulation of both in transparent bath soap is additional protection for the body. This study formulated soaps and determined their antibacterial activity against Staphylococcus aureus, Propionibacterium acnes, and Pseudomonas aeruginosa. Soap was made using the hot process and the antibacterial activity was tested using the agar diffusion. The soap formulas F0 (as the base), F1 (3% clove bud oil), and F2 (a combination of 3% clove bud oil and 0.5% sappan wood ethanolic extract) have good appearance and quality including pH, foam stability, free alkali, unsaponifiable fat, and mineral oil content. The water content in the soap is >15%. The inhibitory diameter values of the soap (F0, F1, and F2) against S. aureus, P. acnes, and P. aeruginosa were in the moderate to strong category. Based on the contact time test of 90 seconds, F0 cannot kill bacteria; F1 can kill Staphylococcus aureus Propionibacterium acnes, and Pseudomonas aeruginosa; F2 killed Staphylococcus aureus in 90 seconds and Propionibacterium acnes, and Pseudomonas aeruginosa in 60 seconds. Keywords: soap, clove bud oil, secang, antibacterial
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