有氧运动和洋甘菊提取物对链脲佐菌素诱导的糖尿病大鼠血清肽C水平的同时影响

N. Mirazi, S. Bayat, A. H. pour, Z. Izadi
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摘要

方法:选取24只雄性Wistar大鼠(体重200±20g),随机分为4组(n=6):对照组(未治疗和训练的糖尿病)、MFE组(用提取物治疗的糖尿病)、有氧训练组(糖尿病和训练)、MFE+有氧训练组(用提取物治疗的糖尿病+有氧训练)。有氧训练在跑步机上进行,为期12周(每周5天,60分钟/天,26米/分钟)。用单剂量链脲佐菌素(65mg/kg bw, ip)诱导大鼠糖尿病。MFE组每日口服(灌胃)200mg/kg并运动,连续12周。资料分析采用ShapiroWilk检验、单因素方差分析和Tukey事后检验,p<0.05为显著水平。
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The Simultaneous Effect of Aerobic Exercise and Matricaria chamomilla L. Flower Extract on the Serum Level of Peptide C in Streptozotocin-Induced Diabetic Rats
Methods: In this experimental study, 24 male Wistar rats (weight range, 200±20g), were randomly divided into 4 groups (n=6): control group (diabetic without treatment and training), MFE (diabetic treated with the extract), aerobic training (diabetic and training), and MFE+aerobic training (diabetic treated with extract+aerobic training). The aerobic training was performed as running on treadmill for 12 weeks (5 days per week, 60min/day, 26meter/min). The rats were diabetized with a single dose of streptozotocin (65mg/kg bw, ip). The MFE groups that daily received 200mg/kg orally (gavaged) along with exercise, were tested for 12 weeks. Data were analyzed using ShapiroWilk test, one way ANOVA, and Tukey post hoc test at the significant level of p<0.05.
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