5年期间神经系统患者住院死亡率的回顾性单中心研究

A. Wiśniewski
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引用次数: 1

摘要

介绍。神经系统疾病多年来一直被认为是危险的,并且与较高的院内死亡风险相关。脑血管疾病被广泛认为是最严重的疾病,与最高的死亡率有关。的目标。该研究的目的是评估5年内在神经内科病房住院的受试者的死亡率,特别是病因、直接原因和死亡的可预测性。材料和方法。本研究为回顾性研究。文件分析涉及最近5年,即2015年至2019年。在比得哥什第一大学医院神经内科住院的8247名患者的整个数据库中,报告和分析了429例死亡。结果。全组死亡率为5.2%,全血管组死亡率为6.6%,非血管组死亡率为1.16%。出血性卒中死亡率最高(28.4%),显著高于缺血性卒中(OR = 6.25, 95% CI 4.9-7.8, p < 0.0001)。卒中患者的死亡率明显高于其他神经系统疾病(OR = 11.08 95% CI 7.7-15.9, p < 0.0001)。死亡的主要直接原因(80%)是由基线疾病引起的原发性脑性疾病。7%的死亡被认为是突然的、意外的,10.7%的死亡与住院期间发生的并发症有关。结论。中风,尤其是出血性中风,仍然是神经内科住院死亡率最高的原因。值得注意的是,应特别注意患有共存传染病的患者,因为这些疾病会导致更高的死亡风险。【关键词】住院死亡率;神经系统疾病;脑卒中;预后
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In-hospital Mortality Among Neurological Patients over the Period of 5 years — a Retrospective, Single-center Study
Introduction. Neurological disorders have been considered for many years dangerous and are associated with higher risk of in-hospital death. Brain vascular disorders are widely considered as the most severe and related to the highest mortality rate. Aim. The aim of the study was to assess the mortality rate in subjects hospitalized in the Neurology ward within 5 years, in particular the etiology, direct cause and predictability of deaths. Material and Methods. This study is retrospective. The documentation analysis concerned the last 5 years, i.e. from 2015 to 2019. From among the entire database of 8247 patients hospitalized in the Neurology Clinic of the University Hospital No. 1 in Bydgoszcz, 429 deaths were reported and analyzed. Results. The mortality rate was 5.2% among all subjects, 6.6% among all vascular patients and 1.16% among non-vascular subjects. The highest mortality was reported among hemorrhagic stroke (28.4%) and it was significantly higher compared to ischemic stroke (OR = 6.25, 95% CI 4.9–7.8, p < 0.0001). Patients with stroke had significantly higher mortality compared to other neurological disorders (OR = 11.08 95% CI 7.7–15.9, p < 0.0001). The main direct reason of death (80%) was primary cerebral as a result of baseline disease. 7% of deaths were considered as sudden, unexpected and 10.7% were related to complications developed during hospitalization. Conclusions. Stroke, especially hemorrhagic subtype, still remains the cause of the highest in-hospital mortality rate in the Neurology Ward. It is worth to notice that special attention should be paid to patients with coexisting infectious diseases, that contribute to higher mortality risk. (JNNN 2020;9(1):20–26) Key Words: in-hospital mortality, neurological disorders, stroke, prognosis
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