两种植物小檗和虎叶的抗糖尿病活性评价

Kouadri Boudjelthia W, Hammadi K, Kouidri M, Djebli N
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引用次数: 7

摘要

本研究是对小檗和木犀草的甲醇提取物和水溶液作为抗糖尿病植物进行价值评价的一部分;在阿尔及利亚广泛使用,特别是在西方地区作为治疗糖尿病的药物。测定两种植物抗氧化活性的方法是通过对总多酚进行定量,得到具有较强抗氧化活性的重要含量,在2 mg/l的甲醇提取物和水溶液中,抑制自由基的比例分别为(83.71%)、(55.35%)、(88.22%)和(75.89%)。降糖剂的α-淀粉酶活性在体外试验中有明显的抑制作用,其中小檗醇提物的α-淀粉酶活性有微弱的抑制作用(89.81%)。
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Evaluation of Antidiabetic Activity of Two Plants Berberis vulgaris and Zygophyllum geslini
This work is part of the valorisation of the methanolic extract and aqueous solutions of Berberis vulgaris and Zygophyllum geslini as antidiabetic plants; widely used in Algeria and more specifically in the region of the West as a remedy for diabetes. The method applied to measure the antioxidant activity is that of trapping of free radicals to the help of DPPH after quantified the total polyphenols revealing an important content with a powerful antioxidant activity in which the percentage of inhibition radical is of (83.71%), (55.35%), (88.22%) and (75.89%) for 2 mg/l of the methanolic extracts and in aqueous of the two plants respectively. While it has been advocated to the test of the α-amylase in vitro for the assessment of the effect antihyperglycemic agent, the results obtained revealed a capacity of remarkable inhibition on the activity of the enzyme with a slight peak for the methanolic extracts of Berberis vulgaris (89.81%).
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