产碳青霉烯酶肠杆菌科在成人重症监护单位肛门拭子中的频率

Augusto J. Vallejos, M. F. Tracogna, Mariana C. Carol Rey, Matías E. Bregant, M. Fernández, M. Cattana, María L Gariboglio Vázquez
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摘要

产生碳青霉烯酶的肠杆菌科(CPE)是全球健康的主要问题之一,主要是那些由质粒编码的肠杆菌。目的是描述CPE在阿根廷查科省一家成人医院重症监护病房(ICU)和COVID-ICU患者肛门拭子中的定植进展。描述性回顾性研究于2021年1月至8月进行,共收集肛拭子379份,检出CPE 26% (n=98)。肺炎克雷伯菌是最常见的分离菌。1月,在COVID-ICU, 18%的肛门拭子呈阳性,全部被确定为KPC碳青霉烯酶。8月,在COVID-ICU,肛门拭子阳性总数上升至81%,检测到的碳青霉烯酶均为MBL型。在ICU,肛门棉签阳性比例从1月的14%上升到8月的49%,同时检测到KPC和MBL碳青霉烯酶。在所有定植的患者中,15%发生CPE感染。必须采取积极的监测和控制措施,以遏制CPE的传播。
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Frecuency of carbapenemase-producing enterobacteriaceae in anal swabs from an adult unit intensive care
The carbapenemase-producing enterobacteriaceae (CPE) are one of the main concerns of global health, mainly those that are encoded by plasmids. The aim was to describe the progress of colonization by CPE in anal swabs of patients of intensive care unit (ICU) and COVID-ICU in an adult hospital from Chaco province, Argentina. A descriptive retrospective study was carried out between 2021 January to August. 379 anal swabs were studied, in 26% (n=98) CPE were detected. K. pneumoniae was the more frequent isolate. In January, in COVID-ICU, 18% of anal swabs where positive, being all identified as KPC carbapenemase. In August, in COVID-ICU, the total of positive anal swab raised to 81% and all detected carbapenemase were MBL type. In ICU, the percentage of positive anal swabs increased from 14% in January to 49% in August, where both KPC and MBL carbapenemases were detected. Of The total of colonized patients, 15% developed CPE infection. Active surveillance and control measures are necessary to keep down the spread of CPE.
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