脂质体是医学和药物输送领域的纳米技术捐助者

Ritesh Kumar Dash, D. Sarangi, Rupak Kumar Swain, Satyajeet Behera
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摘要

脂质体是由一个或多个磷脂双分子层组成的球形囊泡,作为药物载体用于增强药物、营养剂、生物活性剂和许多不同化合物的输送,是一个重要的研究领域。大多数临床批准的囊泡直径为50-300纳米。在一些新的药物传递系统中,脂质体是一种先进的技术,它可以将活性分子传递到作用部位,减少不良副作用,提高其体外和体内活性,降低药物的毒性,提高被封装药物分子的功效。本文就脂质体的特点、优势、可扩展技术及其在食品、化妆品和药品等领域的应用前景作一综述。
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Liposome a Nanotechnological benefactor to the field of Medicine and Drug delivery
Liposomes are spherical vesicles comprises of one or more phospholipid bilayers, which are under substantial research area as drug carriers for enhancing the delivery of drugs, nutritional agents, bioactive agents and many different compounds. The majority of those clinically approved vesicles have diameters of 50–300 nm. Among several new drug delivery systems, liposomes characterize an advanced technology to deliver active molecules to the site of action and decreases undesirable side effects upgrading its in vitro and in vivo activity, as well as reducing the toxicity of the drug and enhancing the efficacy of the encapsulated drug molecule. The present review will briefly explain the characteristics, advantages, scalable techniques based on the type of produced liposomes and potential applications of liposomes in food, cosmetics and pharmaceuticals.
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