腔内支架植入治疗急性和慢性主动脉夹层

T. Shimono, N. Kato, F. Yasuda, Tomoaki Suzuki, U. Yuasa, K. Onoda, T. Hirano, K. Takeda, I. Yada
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引用次数: 126

摘要

背景:腔内支架植入(TSGP)治疗主动脉夹层是一种相对较新的手术方法。我们采用tsgp来封闭主要入口,以治疗和预防主动脉夹层的并发症。分析了早期到中期的结果。方法和结果:37例原发性降主动脉内膜撕裂患者行TSPG术。我们对16例有夹层相关并发症的急性夹层(AOD)进行了TSGP,而不是紧急手术。对8例无并发症的AOD进行治疗,以防止动脉瘤扩大。治疗13例慢性夹层以防止破裂。TSGP在所有病例中都取得了技术上的成功。1例院前破裂死亡。住院死亡率总体为2.7%,合并并发症的AOD为6.3%,无并发症的AOD和慢性夹层为0%。1例持续性内漏需要开放手术,1例内膜撕裂是由支架移植引起的,需要额外的TSGP。初步成功率为94.4%。出院后,在平均24.5个月的随访期间,没有患者死亡或主动脉破裂。3例AOD患者发生支架移植引起的新的内膜撕裂和继发性内膜渗漏。1例开腹手术和2例tsgp手术。总体的精算生存率和2年无心血管事件发生率分别为97.3%和78.3%,合并并发症的AOD为93.8%和48.0%,无并发症的AOD为100%和87.5%,慢性夹层均为100%。结论stsgp是主动脉夹层合理的治疗方案。然而,支架移植引起的延迟内膜撕裂形成是一个需要进一步研究的问题。
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Transluminal Stent-Graft Placements for the Treatments of Acute Onset and Chronic Aortic Dissections
BackgroundTransluminal stent-graft placement (TSGP) for aortic dissection is a relatively new procedure. We performed TSGPs to seal the primary entry site to treat and prevent complications of aortic dissection. The early to mid-term outcomes were analyzed.Methodsand Results—Thirty-seven patients with a primary intimal tear in descending aorta underwent TSPG. TSGP was performed in 16 acute onset dissections (AOD) with dissection-related complications instead of emergency surgery. Eight AOD without complications were treated to prevent aneurysmal enlargement. Thirteen chronic dissections were treated to prevent rupture. TSGP was technically successful in all cases. One patient with prehospital rupture died. The hospital mortality rate was of 2.7% overall, 6.3% in AOD with complications, 0% in AOD without complications and in chronic dissections. One persistent endoleak required open surgery, and 1 intimal tear was caused by the stent-graft, necessitating an additional TSGP. The primary success rate was 94.4% overall. After hospital discharge, no patient died or suffered aortic rupture during an average follow-up of 24.5 months. New intimal tears caused by the stent-grafts and a secondary endoleak developed in 3 AOD patients. One open procedure and 2 additional TSGPs were performed. Actuarial survival rate and cardiovascular event-free rate at 2 years are 97.3% and 78.3% overall, 93.8% and 48.0% in AOD with complications, 100% and 87.5% in AOD without complications, and both 100% in chronic dissections. ConclusionsTSGP is a reasonable treatment option for aortic dissection. However, delayed intimal tear formations caused by the stent-graft is a problem that requires further investigation.
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