{"title":"皮质类固醇诱导的无血管性骨坏死及其与既往COVID-19感染的可能关联","authors":"Kanisha Shah, D. Shukla, R. Khan, S. Malhotra","doi":"10.4103/jopcs.jopcs_56_22","DOIUrl":null,"url":null,"abstract":"Corticosteroid is a frequent implicating factor for the development of avascular bone necrosis (AVN). The etiology of corticosteroid-induced AVN is not fully understood, but it includes fat hypertrophy, fat embolism, and intravascular coagulation that causes obstruction of blood supply to the bone. This association can be carried forward for COVID-19 as well since it is also a microvascular disease. Suffering from COVID-19 and prescription of glucocorticoids could both be responsible for AVN. Early recognition of this complication is essential as the prognosis is affected by the stage of the disease.","PeriodicalId":93784,"journal":{"name":"Journal of primary care specialties : official publication of the Institute of Family Medicine and Primary Care","volume":"28 1","pages":"93 - 96"},"PeriodicalIF":0.0000,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Corticosteroid-induced avascular bone necrosis and possible association with prior COVID-19 infection\",\"authors\":\"Kanisha Shah, D. Shukla, R. Khan, S. Malhotra\",\"doi\":\"10.4103/jopcs.jopcs_56_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Corticosteroid is a frequent implicating factor for the development of avascular bone necrosis (AVN). The etiology of corticosteroid-induced AVN is not fully understood, but it includes fat hypertrophy, fat embolism, and intravascular coagulation that causes obstruction of blood supply to the bone. This association can be carried forward for COVID-19 as well since it is also a microvascular disease. Suffering from COVID-19 and prescription of glucocorticoids could both be responsible for AVN. Early recognition of this complication is essential as the prognosis is affected by the stage of the disease.\",\"PeriodicalId\":93784,\"journal\":{\"name\":\"Journal of primary care specialties : official publication of the Institute of Family Medicine and Primary Care\",\"volume\":\"28 1\",\"pages\":\"93 - 96\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of primary care specialties : official publication of the Institute of Family Medicine and Primary Care\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jopcs.jopcs_56_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of primary care specialties : official publication of the Institute of Family Medicine and Primary Care","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jopcs.jopcs_56_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Corticosteroid-induced avascular bone necrosis and possible association with prior COVID-19 infection
Corticosteroid is a frequent implicating factor for the development of avascular bone necrosis (AVN). The etiology of corticosteroid-induced AVN is not fully understood, but it includes fat hypertrophy, fat embolism, and intravascular coagulation that causes obstruction of blood supply to the bone. This association can be carried forward for COVID-19 as well since it is also a microvascular disease. Suffering from COVID-19 and prescription of glucocorticoids could both be responsible for AVN. Early recognition of this complication is essential as the prognosis is affected by the stage of the disease.
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