一种使用近红外和化学方法对一种苯甲酸草本植物进行化学分解的监控

IF 0.7 Q3 EDUCATION & EDUCATIONAL RESEARCH REMIE-Multidisciplinary Journal of Educational Research Pub Date : 2019-07-09 DOI:10.19184/multijournal.v2i1.20113
Khrisna Agung Cendekiawan, S. Winarso, Ancah Caesarina Novi Marchianti
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引用次数: 4

摘要

2009年关于健康的第36号法律规定,给予社区最广泛的机会加工、生产、分销、开发、改进和使用传统药物,这些药物的益处和安全性是合理的。传统药物(草药)中添加的药用化学物质与治疗剂量不相称,导致过量服用,并造成可能对消费者健康有害的副作用。近红外光谱和化学计量学是检测药物化学物质,特别是地塞米松的分析方法之一。本研究采用描述性非分析性研究设计。本研究采用全抽样法,选取reggency地区28家销售中药(jamu pegal linu)的中药店为研究对象。本研究采用单变量频率分布分析。本研究表明,在近红外分析中,所有中草药样品均未发现地塞米松化学成分,而在化学计量学测试中,发现其中一种中草药样品(代码J-C)中含有2%的地塞米松。向社会宣传使用含药用化学物质的中草药的影响势在必行,同时也需要采用最敏感的方法对其进行分析。关键词:药物滥用,地塞米松,坐骨神经痛中药,近红外,化学计量方法
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Surveilans Penyalahgunaan Bahan Kimia Sintetis Deksametason Pada Jamu Pegal Linu Menggunakan Metode Near Infra Red dan Kemometrik
Law Number 36 of 2009 regarding Health states that the community is given the widest opportunity to process, produce, distribute, develop, improve, and use traditional medicines that can be justified for their benefits and safety. The presence of medicinal chemicals added to traditional medicines (herbs) is not appropriate to the therapeutic dose, resulting in overdosing and causing side effects that can be harmful to the health of the consumers. One of the analytical methods to detect the presence of medicinal chemicals, especially dexamethasone, is the Near Infra Red and Chemometrics method. The research design used in this study was descriptive non-analytic. The population in this study is 28 herbal medicine shop that sells herbal sore-aches traditional medicines (jamu pegal linu) in Jember Regency using the Total Sampling technique. This study is using univariate analysis of frequency distribution. This research shows that there was no chemical content of dexametasone found in all herbal medicine samples in the analysis using the Near Infra Red method while in the Chemometric testing, it was found that one of the herbal samples (code J-C) contained 2% of dexamethasone. It is imperative to Socialize to the community the impact of using herbal medicine containing medicinal chemicals, and it also needs to be analyzed using the most sensitive methods.Keyword: Chemical Abuse, Dexamethasone, Sciatica Herbs, Near Infra Red, Chemometric Methods
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来源期刊
CiteScore
6.40
自引率
2.90%
发文量
5
审稿时长
20 weeks
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