影响吞噬刺激下猪白细胞葡萄糖氧化的因素

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-09-01 DOI:10.1016/S0300-872X(76)80068-6

H. Buschmann , B. Frohnwieser

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引用次数: 0

摘要

研究了细菌和惰性颗粒吞噬过程中对猪白细胞D-(1-14C)葡萄糖和D-(6-14C)葡萄糖代谢的刺激作用。得到了以下结果:1。吞噬刺激下葡萄糖氧化的强度与添加颗粒的性质和数量直接相关。活的细菌比同样数量的热死生物更能刺激葡萄糖代谢。至于刺激的程度，提供吞噬作用的细菌种类是至关重要的。体外添加脂多糖后，观察到刺激作用，添加氢化可的松后显示出抑制作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Factors Influencing the Phagocytosis - Stimulated Glucose Oxidation in Porcine Leukocytes

The stimulation of the D-(1-¹⁴C)glucose and D-(6-¹⁴C)glucose metabolism in pig leucocytes during the phagocytosis of bacteria and inert particles was studied. The following results were obtained:

1. The magnitude of phagocytosis-stimulated glucose oxidation is directly related to the nature and number of particles added.

2. Live bacteria stimulate the glucose metabolism to a greater extent than do a similar number of heat-killed organisms. As to the extent of the stimulation the species of bacteria offered for phagocytosis is crucial.

3. After in vitro addition of a lipopolysaccharide a stimulating effect is observed, a depression has been shown after the addition of hydrocortisone.

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