激光综合治疗实验性骨膜炎不同时期形态学检查结果的比较

T. Tserakhava, I. Pohodenko-Chudakova, N. Nijiati, O. Yudina
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摘要

目标。目的:比较评价激光照射在实验性颌骨骨膜炎术后治疗中不同时期感染病灶、炎症灶形态计量学研究和微循环床血管密度的结果。材料和方法。实验对象为56只家兔。模拟急性下颌骨化脓性骨膜炎(APP) 54例。所有的动物都被分为以下几个系列。1 - 12系列家兔,APP模型建立后,分别于术后第1、3、5天进行激光治疗。2 - 16组家兔分别于术后第3、5、7天接受激光治疗。第三组(对照组):APP模型建立后未处理的26只家兔。以颌骨碎片为标准的系列4 - 2动物。结果。在所有系列1微制剂中,实验完成后的变化均可表现为轻度残余炎症。骨膜炎的综合治疗,包括激光治疗,从术后第一天开始应用,可以有效缓解感染性炎症,为组织再生创造最佳条件。结论。尽管在系列1和系列2中,利用激光对炎症病灶的影响治疗实验性骨膜炎的复杂术后治疗方案相似,但研究发现,其积极影响是由于术后尽早使用具有更大程度的互补性。
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COMPARISON OF THE RESULTS OF MORPHOLOGICAL EXAMINATION AT DIFFERENT PERIODS OF LASER THERAPY INTEGRATION INTO COMPLEX TREATMENT FOR EXPERIMENTAL PERIOSTITIS
Objectives. To carry out a comparative assessment of the results of morphometric study of infectious and inflammatory focus and the density of vessels of the microcirculatory bed at different periods of laser radiation application in the postoperative treatment for experimental periostitis of the jaws. Material and methods. The experiment was performed on 56 rabbits. 54 of them had simulated acute purulent periostitis (APP) of the lower jaw. All the animals were divided into the following series. Series 1 - 12 rabbits which, after the creation of the APP model, were treated with laser therapy on the 1st, the 3rd and the 5th days after surgery. Series 2 - 16 rabbits which underwent laser therapy treatment on the 3rd, the 5th and the 7th days after surgery. Series 3 (control) - 26 rabbits which were not treated after the creation of the APP model. Series 4 - 2 animals whose jaw fragments were taken as a standard. Results. In all series 1 micropreparations, after completing the experiment the changes can be characterized as minimally residual inflammatory ones. Complex treatment of periostitis, including laser treatment, applied from the first day of the postoperative period, is effective for relieving infectious inflammation and creating optimal conditions for tissue regeneration. Conclusions. Despite the similarity of the schemes of complex postoperative treatment for experimental periostitis using the effect of laser on the focus of inflammation in series 1 and 2, it has been found that its positive influence is due to a greater degree of complementarity when used as early as possible after surgery.
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