血源性诱导多能干细胞(iPSCs):益处、挑战和未来之路。

Journal of Alzheimer's disease & Parkinsonism Pub Date : 2016-10-25 DOI:10.4172/2161-0460.1000275

Jimmy A El Hokayem, H. N. Cukier, D. Dykxhoorn

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引用次数: 27

摘要

自十年前诱导多能干细胞(iPSCs)诞生以来，数百篇出版物已经证明了它们对疾病建模和治疗的重大影响。在这篇评论中，我们将总结iPSC领域的关键里程碑、利益和挑战。此外，我们将强调在我们实验室和其他实验室所做的工作中，血液是一种有效且易于获取的患者特异性iPSCs来源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Blood Derived Induced Pluripotent Stem Cells (iPSCs): Benefits, Challenges and the Road Ahead.

Since the creation of induced Pluripotent Stem Cells (iPSCs) ten years ago, hundreds of publications have demonstrated their considerable impact on disease modeling and therapy. In this commentary, we will summarize key milestones, benefits and challenges in the iPSC field. Furthermore, we will highlight blood as an effective and easily accessible source for patient-specific iPSCs derivation in the context of work done in our laboratory and others.

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Journal of Alzheimer's disease & Parkinsonism

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