刚地弓形虫细胞外囊泡作用的研究进展

Carlos J. Ramrez-Flores, Ricardo Mondragn-Flores
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引用次数: 2

摘要

刚地弓形虫是世界上最成功的病原体之一。它的高分泌能力与其在被感染宿主体内的运动、侵袭和组织传播动力学有关。弓形虫是一种高分泌性的寄生虫,从分泌细胞器中释放蛋白质,如微粒体、形虫体和致密颗粒,但它也分泌/排泄大量各种作用未知的细胞外囊泡。本文就弓形虫释放的细胞外囊泡大小不同、鉴定名称不同、可能具有的生物学功能等特点进行了讨论
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Elucidating the Role of Extracellular Vesicles Released by Toxoplasma gondii: A Review
Toxoplasma gondii is one of the most successful pathogens worldwide. Its high secretory capability is related to its dynamics for motility, invasion and tissue dissemination within the infected host. Toxoplasma is a highly secretory parasite of proteins released from secretory organelles such as micronemes, rhoptries and dense granules, but it also secretes/excretes a huge variety of extracellular vesicles with unknown role. Herein, it is discussed some characteristics of the extracellular vesicles released by Toxoplasma, such as their different sizes, different identification names, and their possible biological functions
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