无监督自我药物流产失败的原因:来自印度北部的研究

A. Mishra, S. Malik, R. Dewan, Swati Gupta, R. Hooda
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摘要

引言:不安全堕胎导致8%的孕产妇死亡。人工流产药物的易得性和滥用导致人工流产相关并发症激增。本研究旨在了解在药物流产发生并发症或流产失败后来我中心就诊的妇女的概况、知识、态度及选择自行流产的原因。我们也试图评估不同并发症的负担和失败的原因的自我引产药物流产。材料和方法:这是一项前瞻性混合方法研究,在三级保健中心的妇产科进行。两名医生在预先编制的问卷的帮助下对这些妇女进行了访谈,并从医院记录中记下了她们的诊断、治疗过程和住院时间。结果:我们收集了216例因自身药物流产并发症而来我院就诊的妇女。92名妇女使用米非司酮和米索前列醇方案,其余妇女使用米索前列醇方案。165名妇女从药剂师那里购买了非处方药物。信息的主要来源是丈夫或朋友。多数患者(n= 87.9%)认为低危。97%患者用药计划不正确,仅口服米索前列醇。宫外孕破裂、贫血、败血症、不完全流产、漏产和继续妊娠分别占1.8%、69.44%、8.3%、68.5%、9.7%和23.14%。结论:忽视合格标准和用药方案不当是导致自行药物流产失败的最常见原因。低感知风险和不愿去医院和干预是最常见的原因选择自己流产。
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Factors behind failure of unsupervised self induced medical abortion : A Study from North India
Introduction : Unsafe abortions contribute to 8% of maternal mortality. Easy availability and rampant use of medical methods of abortion lead to upsurge in self induced abortion related complications. Present study was conducted to assess the profile, knowledge, attitude and reasons of preference of self induced abortion in women visiting our centre after complication or failure of medical abortion. We also tried to evaluate the burden of different complications and factors behind failure of self induced medical abortion. Material and Methods: It was a prospective mixed methods study performed in the department of obstetrics and gynaecology at a tertiary care centre. These women were interviewed by two doctors with the help of pre structured questionainare and their diagnosis, course of management and duration of stay in the hospital was noted down from hospital records. Results: We recruited 216 women visiting our facility after some complication of self induced medical abortion. 92 women used Mifepristone and misoprostol regimen and rest used misoprostol. 165 women have purchased drugs over the counter from pharmacists. Major source of information is husband or friends. Most of the patients [n= 87.9%] consider it low risk.97% patients follow incorrect drug schedule and misoprostol was taken by oral route only. Ruptured ectopic pregnancy, anaemia, Sepsis, Incomplete abortion, Missed abortion and continuation of pregnancy was observed in 1.8%, 69.44%, 8.3%, 68.5 %, 9.7% and 23.14%. Conclusion: Neglect of eligibility criteria and faulty drug regimens are the most common reasons for failure on self induced medical abortions. Low perceived risk and reluctance to hospital visit and interventions are most common reasons of preference of self induced abortions.
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